| 单词 | PAPP-alpha |
| 释义 | PAPP-alpha《英文msh词典》PAPP-alpha [入口词] PAPP-alpha [主题词] Pregnancy-Associated Plasma Protein-A [英文释义] A product of the PLACENTA,and DECIDUA,secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS,ovarian FOLLICULAR FLUID,and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500 kDa. |
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