《英文msh词典》Paraneoplastic Cerebellar Syndromes
[入口词] Paraneoplastic Cerebellar Syndromes
[主题词] Paraneoplastic Cerebellar Degeneration
[英文释义] Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al.,Principles of Neurology,6th ed,p686)