| 单词 | Pentoxyresorufin O-Dealkylase |
| 释义 | Pentoxyresorufin O-Dealkylase《英文msh词典》Pentoxyresorufin O-Dealkylase [同义词] Pentoxyresorufin O-Dealkylase [主题词] Cytochrome P-450 CYP2B1 [中文释义] 五羟试卤灵O-脱烷基酸 [英文释义] A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin,TESTOSTERONE,and ANDROSTENEDIONE. This enzyme,encoded by CYP2B1 gene,also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS. |
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