单词 | Autoimmune Syndrome Type II,Polyglandular |
释义 | Autoimmune Syndrome Type II,Polyglandular《英文msh词典》Autoimmune Syndrome Type II,Polyglandular [同义词] Autoimmune Syndrome Type II,Polyglandular [主题词] Polyendocrinopathies,Autoimmune [中文释义] 自身免疫性综合征Ⅱ型,多内分泌腺 [英文释义] Autoimmune disease affecting multiple endocrine organs. Type I is characterized by childhood onset and mucocutaneous candidiasis,while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE),lymphocytic thyroiditis,hypoparathyroidism,and gonadal failure. In both types organ-specific antibodies against a variety of endocrine glands have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes,onset is usually in adulthood,and candidiasis is not present. |
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