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单词 Polyendocrinopathy,Autoimmune
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Polyendocrinopathy,Autoimmune


《英文msh词典》Polyendocrinopathy,Autoimmune
[入口词] Polyendocrinopathy,Autoimmune
[主题词] Polyendocrinopathies,Autoimmune
[英文释义] Autoimmune disease affecting multiple endocrine organs. Type I is characterized by childhood onset and mucocutaneous candidiasis,while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE),lymphocytic thyroiditis,hypoparathyroidism,and gonadal failure. In both types organ-specific antibodies against a variety of endocrine glands have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes,onset is usually in adulthood,and candidiasis is not present.
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