| 单词 | Autosomal Dominant Optic Atrophy |
| 释义 | Autosomal Dominant Optic Atrophy《英文msh词典》Autosomal Dominant Optic Atrophy [入口词] Autosomal Dominant Optic Atrophy [主题词] Optic Atrophy,Autosomal Dominant [中文释义] 常染色体显性视神经萎缩 [英文释义] Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity,color vision deficits,a centrocecal scotoma,and optic nerve pallor (Hum. Genet. 1998; 102: 79-86). Mutations leading to this condition have been mapped to the OPA1 gene at chromosome 3q28-q29. OPA1 codes for a dynamin-related GTPase that localizes to mitochondria. |
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