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单词 Proteins abl,Proto-Oncogene
释义

Proteins abl,Proto-Oncogene


《英文msh词典》Proteins abl,Proto-Oncogene
[入口词] Proteins abl,Proto-Oncogene
[主题词] Proto-Oncogene Proteins c-abl
[英文释义] Non-receptor tyrosine kinases encoded by the c-abl gene. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal hematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted,releasing the kinase from negative regulation.
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