《英文msh词典》Proto Oncogene Protein c kit
[入口词] Proto Oncogene Protein c kit
[主题词] Proto-Oncogene Protein c-kit
[英文释义] A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic,gonadal,and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM,while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.