《英文MSH词典》AY 22 989
[入口词] AY 22 989
[主题词] Sirolimus
[药动学] Immunosuppressive Agents
[英文释义] A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.