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单词 Receptor,GABA-B
释义

Receptor,GABA-B


《英文msh词典》Receptor,GABA-B
[入口词] Receptor,GABA-B
[主题词] Receptors,GABA-B
[英文释义] Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically,and act variously by inhibition of adenylate cyclase,activation of phospholipase A2,activation of potassium channels,and inactivation of voltage-activated calcium channels.
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