单词 | Receptor,SCF |
释义 | Receptor,SCF《英文msh词典》Receptor,SCF [入口词] Receptor,SCF [主题词] Proto-Oncogene Protein c-kit [英文释义] A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic,gonadal,and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM,while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. |
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