《英文msh词典》Receptors,erbB 2
[入口词] Receptors,erbB 2
[主题词] Receptor,erbB-2
[英文释义] A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR,EPIDERMAL GROWTH FACTOR),the erbB-3 receptor (RECEPTOR,ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.