《英文msh词典》Receptors,Thrombin
[主题词] Receptors,Thrombin
[同义词] Thrombin Receptors
[入口词] TRAP Peptide
[入口词] Thrombin Receptor
[入口词] Thrombin Receptor Activating Peptide Ligand
[入口词] Thrombin Receptor Activating Peptides
[入口词] Thrombin Receptor Activator Peptide
[入口词] Peptide,TRAP
[入口词] Receptor,Thrombin
[中文释义] 受体,凝血酶
[英文释义] A family of proteinase-activated receptors that are specific for THROMBIN. They are found primarily on PLATELETS and on ENDOTHELIAL CELLS. Activation of thrombin receptors occurs through the proteolytic action of THROMBIN,which cleaves the N-terminal peptide from the receptor to reveal a new N-terminal peptide that is a cryptic ligand for the receptor. The receptors signal through HETEROTRIMERIC GTP-BINDING PROTEINS. Small synthetic peptides that contain the unmasked N-terminal peptide sequence can also activate the receptor in the absence of proteolytic activity.