单词 | Reductase,NADH Methemoglobin |
释义 | Reductase,NADH Methemoglobin《英文msh词典》Reductase,NADH Methemoglobin [入口词] Reductase,NADH Methemoglobin [主题词] Cytochrome-B(5) Reductase [英文释义] A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane,where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA. |
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