| 单词 | 25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase |
| 释义 | 25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase《英文msh词典》25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase [入口词] 25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase [主题词] 25-Hydroxyvitamin D3 1-alpha-Hydroxylase [中文释义] 25-羟维生素D(3)1α-羟化酶 [英文释义] A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP27B1 gene,converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol). |
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