| 单词 | RNA Binding Protein FUS |
| 释义 | RNA Binding Protein FUS《英文msh词典》RNA Binding Protein FUS [入口词] RNA Binding Protein FUS [主题词] RNA-Binding Protein FUS [英文释义] A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator,while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS,FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA,MYXOID) and acute myeloid leukemia. |
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