《英文msh词典》RNA,Small Interfering
[主题词] RNA,Small Interfering
[同义词] Small Interfering RNA
[同义词] siRNA
[入口词] Interfering RNA,Small
[英文释义] Small ANTISENSE RNAs (20 -25 nucleotides) that are generated from specific dsRNAs (RNA,DOUBLE-STRANDED) which trigger targeted mRNA (RNA,MESSENGER) degradation (RNA INTERFERENCE). They serve as guides for the cleavage of homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. The same ribonuclease,Dicer,that is required for processing of the dsRNAs to siRNA is also involved in processing MICRORNAS (miRNAs) from their precursor RNAs.