| 单词 | Silent Information Regulator Proteins,Saccharomyces cerevisiae |
| 释义 | Silent Information Regulator Proteins,Saccharomyces cerevisiae《英文msh词典》Silent Information Regulator Proteins,Saccharomyces cerevisiae [主题词] Silent Information Regulator Proteins,Saccharomyces cerevisiae [同义词] SIR Proteins,S cerevisiae [入口词] Silent Information Regulator Proteins,S cerevisiae [入口词] Silent Mating Type Information Regulator Protein,S cerevisiae [英文释义] A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous,interacting proteins,Sir1p,Sir2p,Sir3p,and Sir4p. Sir2p,an NAD-dependent HISTONE DEACETYLASE,is the founding member of the family of SIRTUINS. |
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