《英文msh词典》Steele-Richardson-Olszewski Disease
[入口词] Steele-Richardson-Olszewski Disease
[主题词] Supranuclear Palsy,Progressive
[英文释义] A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al.,Principles of Neurology,6th ed,pp1076-7)