《英文msh词典》Acetylhydrolase II,PAF
[入口词] Acetylhydrolase II,PAF
[主题词] 1-Alkyl-2-acetylglycerophosphocholine Esterase
[英文释义] A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position,but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA,and HYPERCHOLESTEROLEMIA.