《英文msh词典》Storage Diseases,Ganglioside
[入口词] Storage Diseases,Ganglioside
[主题词] Gangliosidoses
[英文释义] A group of often fatal inherited diseases marked by the accumulation of GANGLIOSIDES in LYSOSOMES secondary to enzymatic deficiency states. Gangliosidoses include TAY-SACHS DISEASE; GANGLIOSIDOSIS GM1; GANGLIOSIDOSES GM2; and SANDHOFF DISEASE; which share the infantile or childhood onset of CENTRAL NERVOUS SYSTEM deterioration. (Menkes,Textbook of Child Neurology,5th ed,pp89-97)