单词 | Sulfoximine,Buthionine |
释义 | Sulfoximine,Buthionine《英文msh词典》Sulfoximine,Buthionine [入口词] Sulfoximine,Buthionine [主题词] Buthionine Sulfoximine [药动学] Radiation-Sensitizing Agents [英文释义] A synthetic amino acid that depletes glutathione by irreversibly inhibiting gamma-glutamylcysteine synthetase. Inhibition of this enzyme is a critical step in glutathione biosynthesis. It has been shown to inhibit the proliferative response in human T-lymphocytes and inhibit macrophage activation. (J Biol Chem 1995;270(33):1945-7) |
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