单词 | Switching,Isotype |
释义 | Switching,Isotype《英文msh词典》Switching,Isotype [入口词] Switching,Isotype [主题词] Immunoglobulin Class Switching [英文释义] Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing. |
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