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单词 Syndromes,Adrenogenital
释义

Syndromes,Adrenogenital


《英文msh词典》Syndromes,Adrenogenital
[入口词] Syndromes,Adrenogenital
[主题词] Adrenal Hyperplasia,Congenital
[英文释义] A group of syndromes caused by inherited defects in cortisol (HYDROCORTISONE) and/or ALDOSTERONE biosynthesis. There are several types including simple virilizing forms (adrenogenital syndrome),salt-wasting forms,and virilizing hypertension forms depending on the enzyme of defects. Defects in STEROID 21-HYDROXYLASE are most common. Other defects occur in STEROID 11-BETA-HYDROXYLASE,STEROID 17-ALPHA-HYDROXYLASE,or 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES).
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