《英文msh词典》Acid,3-Hydroxy-3-methylglutaric
[入口词] Acid,3-Hydroxy-3-methylglutaric
[主题词] Meglutol
[药动学] Hydroxymethylglutaryl-CoA Reductase Inhibitors
[英文释义] An antilipemic agent which lowers cholesterol,triglycerides,serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.