| 单词 | Thrombin Receptor Activator Peptide |
| 释义 | Thrombin Receptor Activator Peptide《英文msh词典》Thrombin Receptor Activator Peptide [入口词] Thrombin Receptor Activator Peptide [主题词] Receptors,Thrombin [英文释义] A family of proteinase-activated receptors that are specific for THROMBIN. They are found primarily on PLATELETS and on ENDOTHELIAL CELLS. Activation of thrombin receptors occurs through the proteolytic action of THROMBIN,which cleaves the N-terminal peptide from the receptor to reveal a new N-terminal peptide that is a cryptic ligand for the receptor. The receptors signal through HETEROTRIMERIC GTP-BINDING PROTEINS. Small synthetic peptides that contain the unmasked N-terminal peptide sequence can also activate the receptor in the absence of proteolytic activity. |
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