《英文msh词典》TIMP-3,Human
[入口词] TIMP-3,Human
[主题词] Tissue Inhibitor of-Metalloproteinase-3
[药动学] Protease Inhibitors
[英文释义] A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21 kD,nonglycosylated protein. TIMP-3 does not show a high degree of structural similarity unlike TIMP-1 and TIMP-2 which are structurally similar. However,it does possess a high degree of structural similarity with that of chicken TIMP-3 (ChIMP-3). Human TIMP-3 is of particular concern because of its potential role in cancer,arthritis,and eye diseases.