| 单词 | beta-3,Integrin alpha-IIb |
| 释义 | beta-3,Integrin alpha-IIb《英文msh词典》beta-3,Integrin alpha-IIb [入口词] beta-3,Integrin alpha-IIb [主题词] Platelet Glycoprotein GPIIb-IIIa Complex [英文释义] Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such,it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA. |
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