| 单词 | Ubiquitin Protein Ligase Complexes |
| 释义 | Ubiquitin Protein Ligase Complexes《英文msh词典》Ubiquitin Protein Ligase Complexes [入口词] Ubiquitin Protein Ligase Complexes [主题词] Ubiquitin-Protein Ligase Complexes [英文释义] Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES),conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES),and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES). |
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