单词 | v myb Oncogenes |
释义 | v myb Oncogenes《英文msh词典》v myb Oncogenes [入口词] v myb Oncogenes [主题词] Genes,myb [英文释义] Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts,Dictionary of Cytokines,1995). |
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