《英文msh词典》Zinc Finger Motifs
[入口词] Zinc Finger Motifs
[主题词] Zinc Fingers
[英文释义] Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger,one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif,zinc fingers can form a large number of different sequence specific binding sites.