| 单词 | 11-beta-Hydroxysteroid Dehydrogenase Type 2 |
| 释义 | 11-beta-Hydroxysteroid Dehydrogenase Type 2《英文msh词典》11-beta-Hydroxysteroid Dehydrogenase Type 2 [主题词] 11-beta-Hydroxysteroid Dehydrogenase Type 2 [入口词] 11 beta-HSD2 [入口词] 11 beta-Hydroxysteroid Dehydrogenase Type 2 [入口词] 11beta-HSD2 [入口词] 11beta-HSD2 Reductase [入口词] 11beta-Hydroxysteroid Dehydrogenase Type 2 [入口词] 11 beta Hydroxysteroid Dehydrogenase Type 2 [入口词] 11beta Hydroxysteroid Dehydrogenase Type 2 [英文释义] An high-affinity,NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts undirectionally to catalyze the dehdrogenation of CORTISOL to CORTISONE. It is found predominantly in mineralocorticoid target tissues such as the KIDNEY; COLON; SWEAT GLANDS; and the PLACENTA. Absence of the enzyme leads to a fatal form of childhood hypertension termed,APPARENT MINERALOCORTICOID EXCESS SYNDROME. |
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