《英文msh词典》Blood Coagulation Factor I
[入口词] Blood Coagulation Factor I
[主题词] Fibrinogen
[英文释义] Plasma glycoprotein clotted by thrombin,composed of a dimer of three non-identical pairs of polypeptide chains (alpha,beta,gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B,the proteolytic action of other enzymes yields different fibrinogen degradation products.