| 单词 | BRCA2 Genes |
| 释义 | BRCA2 Genes《英文msh词典》BRCA2 Genes [入口词] BRCA2 Genes [主题词] Genes,BRCA2 [中文释义] BRCA2基因 [英文释义] A tumor suppressor gene (GENES,SUPPRESSOR,TUMOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large,nuclear protein that is an essential component of DNA repair pathways,suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6) |
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