| 单词 | c-abl,Proto-Oncogene Proteins |
| 释义 | c-abl,Proto-Oncogene Proteins《英文msh词典》c-abl,Proto-Oncogene Proteins [入口词] c-abl,Proto-Oncogene Proteins [主题词] Proto-Oncogene Proteins c-abl [英文释义] Non-receptor tyrosine kinases encoded by the c-abl gene. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal hematopoiesis especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted,releasing the kinase from negative regulation. |
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