单词 | CD42a Antigens |
释义 | CD42a Antigens《英文msh词典》CD42a Antigens [同义词] CD42a Antigens [主题词] Platelet Glycoprotein GPIb-IX Complex [中文释义] CD42a抗原 [英文释义] Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides,GPIb alpha,GPIb beta,and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome. |
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