《英文msh词典》CD4 Antigens
[同义词] CD4 Antigens
[主题词] Antigens,CD4
[中文释义] CD4抗原
[英文释义] 55-kD Glycoproteins originally defined as differentiation antigens on T-lymphocytes,but also found on other cells including monocytes/macrophages. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MHC (Major Histocompatibility Complex) Class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as HIV receptors,binding directly to the envelope protein gp120 on HIV.