《英文msh词典》Adenomatous Polyposis,Familial
[入口词] Adenomatous Polyposis,Familial
[主题词] Adenomatous Polyposis Coli
[英文释义] A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES,APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.