| 单词 | c-erbA Proto-Oncogenes |
| 释义 | c-erbA Proto-Oncogenes《英文msh词典》c-erbA Proto-Oncogenes [入口词] c-erbA Proto-Oncogenes [主题词] Genes,erbA [英文释义] Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS,AVIAN),v-erbA. In cells,erbA genes encode thyroid hormone receptors (RECEPTORS,THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsivenss but not DNA binding capacity. |
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