单词 | Cerebellar Degeneration,Paraneoplastic |
释义 | Cerebellar Degeneration,Paraneoplastic《英文msh词典》Cerebellar Degeneration,Paraneoplastic [同义词] Cerebellar Degeneration,Paraneoplastic [主题词] Paraneoplastic Cerebellar Degeneration [中文释义] 小脑变性,副肿瘤性 [英文释义] Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al.,Principles of Neurology,6th ed,p686) |
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