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单词 Cerebellar Syndromes,Paraneoplastic
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Cerebellar Syndromes,Paraneoplastic


《英文msh词典》Cerebellar Syndromes,Paraneoplastic
[入口词] Cerebellar Syndromes,Paraneoplastic
[主题词] Paraneoplastic Cerebellar Degeneration
[英文释义] Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al.,Principles of Neurology,6th ed,p686)
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