《英文msh词典》c-kit Receptor
[同义词] c-kit Receptor
[主题词] Proto-Oncogene Protein c-kit
[中文释义] c-kit受体
[英文释义] A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic,gonadal,and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM,while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.