《英文msh词典》c-met Protein
[入口词] c-met Protein
[主题词] Proto-Oncogene Protein c-met
[英文释义] A cell surface protein-tyrosine kinase receptor for HEPATOCYTE GROWTH FACTOR. It consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEIN C-MET are associated with papillary renal carcinoma and other neoplasia.