| 单词 | 12-HETE |
| 释义 | 12-HETE《英文MSH词典》12-HETE [同义词] 12-HETE [主题词] 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid [英文释义] A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51) |
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