《英文msh词典》5 HT1Dbeta Receptor
[入口词] 5 HT1Dbeta Receptor
[主题词] Receptor,Serotonin,5-HT1B
[英文释义] A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.