单词 | 5-Hydroxytryptamine 1B Receptor |
释义 | 5-Hydroxytryptamine 1B Receptor《英文msh词典》5-Hydroxytryptamine 1B Receptor [入口词] 5-Hydroxytryptamine 1B Receptor [主题词] Receptor,Serotonin,5-HT1B [英文释义] A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect. |
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