《英文msh词典》Cyclin Dependent Kinase 1
[入口词] Cyclin Dependent Kinase 1
[主题词] CDC2 Protein Kinase
[英文释义] Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.