《英文msh词典》Cystatins,Kininogen
[同义词] Cystatins,Kininogen
[主题词] Kininogens
[药动学] Cysteine Proteinase Inhibitors
[中文释义] 西司他汀,激肽原
[英文释义] Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation,blood clotting,complement reactions,etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.