《英文msh词典》Cytochrome P-450c11AS
[入口词] Cytochrome P-450c11AS
[主题词] Aldosterone Synthase
[英文释义] A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme,encoded by CYP11B2 gene,is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.