| 单词 | Cytochrome P-450(c-21) |
| 释义 | Cytochrome P-450(c-21)《英文msh词典》Cytochrome P-450(c-21) [入口词] Cytochrome P-450(c-21) [主题词] Steroid 21-Hydroxylase [英文释义] An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP21 gene,converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA,CONGENITAL). |
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